Astrocytes Stimulate Microglial Proliferation and M2 Polarization In Vitro through Crosstalk between Astrocytes and Microglia

Astrocytes and Microglial Cells: Modulation ATP Mediates Calcium Signaling Between

Abstract Astrocytes Modulate Microglial Phenotype and Dendritic Cell-like Properties Astrocytes Modulate Microglial Phenotype and Dendritic Cell-like Properties Astrocytes Modulate Microglial Phenotype and Dendritic Cell-like Properties

ASTROCYTES MODULATE MICROGLIAL PHENOTYPE AND DENDRITIC CELL-LIKE PROPERTIES by Nischal K. Padala Microglia are the resident immune cells of the CNS. In the healthy CNS, they express negligible levels of MHC II molecules as well as co-stimulatory molecules CD40, CD80 and CD86 necessary for antigen presentation to and activation of T cells. Co-stimulatory molecule expression can be induced in iso...

P158: Targeting of Microglial M1/M2 Polarization Through Stem Cells Therapy as A Promising Candidate in Traumatic Brain Injury (TBI)

Traumatic brain injury is a serious global health problem with irreversible high morbidity and disability and Because of its unknown pathophysiological mechanisms, efficient therapeutic approaches to improve the poor outcome and long-term impairment of behavioral function are still remains lacking. The microglial cells are the resident macrophage cells of the brain and have M1/M2 phenotype, for...

Policing the police: astrocytes modulate microglial activation.

Andy Y. Shih,1,2,3 Herman B. Fernandes,1,2,3 Fiona Y. Choi,1,2,3 Michael G. Kozoriz,4 Yingru Liu,1,3 Ping Li,1,2 Catherine M. Cowan,2,3 and Andis Klegeris2 1Graduate Program in Neuroscience, 2Kinsmen Laboratory of Neurological Research, 3Brain Research Centre, and 4Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3 Revi...

P95: Targeting of Microglial M1/M2 Polarization through Stem Cells Therapy as a Promising Candidate in Traumatic Brain Injury (TBI)

Traumatic brain injury is a serious global health problem with irreversible high morbidity and disability and Because of its unknown pathophysiological mechanisms, efficient therapeutic approaches to improve the poor outcome and long-term impairment of behavioral function are still remains lacking. The microglial cells are the resident macrophage cells of the brain and have M1/M2 phenotype, for...